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Vermox (Mebendazole)
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Vermox

Vermox is used to treat infections caused by worms such as whipworm, pinworm, roundworm, and hookworm. It is also used to treat infections caused by more than one of these worms at the same time.

Other names for this medication:

Similar Products:
Albenza, Zentel, Andazol, Ivermectin, Stromectol, Biltricide, Pin-X, Antiminth, Ascarel, Impavido, Mintezol, Pinworm Caplets, Reese's Pinworm Medicine

 

Also known as:  Mebendazole.

Description

Vermox is used to treat infections caused by worms such as whipworm, pinworm, roundworm, and hookworm. It is also used to treat infections caused by more than one of these worms at the same time.

Vermox is an antihelmintic, or anti-worm, medication. It prevents worms from growing or multiplying in your body.

Vermox is also known as Mebendazole, Ovex, Antiox, Pripsen, Mebex, Wormin.

Dosage

Vermox tablets may be swallowed, chewed, or crushed and mixed with food.

It may be up to 3 days after treatment before the worm is removed from your stomach and intestines. The amount of time it takes to cure the infection depends on how susceptible the worm is to Vermox, and how quickly your own digestive system is moving. If the infection has not been cured within 3 weeks, a second treatment may be necessary.

Treatment of family members and other close contacts may be necessary. Pinworm is spread very easily to others in close contact with the infected person.

If you want to achieve most effective results do not stop taking Vermox suddenly.

Overdose

If you overdose Vermox and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Vermox are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Vermox if you are allergic to its components.

Do not take Vermox if you are pregnant, planning to become pregnant. Do not breast-feed while taking Vermox.

Children younger than 2 years of age should not take mebendazole unless otherwise directed by your doctor.

It can be dangerous to stop Vermox taking suddenly.

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A 70-year old female, until recently a resident of the rural Philippines, underwent coronary bypass grafting in New York City. Nine hours after surgery (one hour after endotracheal extubation), cough and arterial oxygen desaturation prompted airway suctioning, which retrieved an adult nematode from the posterior oroharynx. symptomes abated immediately, after which the patient receive a curative course of mebendazole.

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The efficacy of MEB, as assessed by FECR, was determined in six trials involving 5,830 school children in Brazil, Cambodia, Cameroon, Ethiopia, United Republic of Tanzania, and Vietnam. The efficacy of MEB was compared to that of ALB as previously assessed in 8,841 school children in India and all the above-mentioned study sites, using identical methodologies.

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One hundred sixty-two children aged 5 to 16 years whose parents complained about their chronic bad breath.

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Improvement of FLBZ aqueous solubility due to CDs resulted markedly higher than that observed for mebendazole and albendazole. However, oppositely to what was expected, the absorption-related pharmacokinetic parameters did not show any marked formulation-dependant effect. After the i.a. administration of FLBZ, the AUC and the Tmax of the parent compound were significantly (P < 0.05) reduced, which is consistent with ruminal bypass.

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The rate of major congenital defects was not significantly higher in the mebendazole group than in the control group (97 [1.8%] of 5275 vs 26 [1.5%] of 1737; odds ratio 1.24 [95% CI 0.8-1.91], p=0.39). Among 407 women who had taken mebendazole in the first trimester (contrary to medical advice), 10 (2.5%) had major congenital defects (odds ratio vs controls 1.66 [0.81-3.56], p=0.23). The proportions of stillbirths and perinatal deaths were significantly lower in the mebendazole group (1.9 vs 3.3%, 0.55 [95% CI 0.4-0.77]), as was the proportion of low-birthweight babies (1.1 vs 2.3%, 0.47 [95% CI 0.32-0.71]).

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The metacestode stage of Echinococcus multilocularis is the causative agent of alveolar echinococcosis (AE), a parasitic disease affecting the liver, with occasional metastasis into other organs. Benzimidazole carbamate derivatives such as mebendazole and albendazole are currently used for chemotherapeutic treatment of AE. Albendazole is poorly resorbed and is metabolically converted to its main metabolite albendazole sulfoxide, which is believed to be the active component, and further to albendazole sulfone. Chemotherapy with albendazole has been shown to have a parasitostatic rather than a parasitocidal effect; it is not effective in all cases, and the recurrence rate is rather high once chemotherapy is stopped. Thus, development of new means of chemotherapy of AE is needed. This could include modifications of benzimidazoles and elucidiation of the respective biological pathways. In this study we performed in vitro drug treatment of E. multilocularis metacestodes with albendazole sulfoxide and albendazole sulfone. High-performance liquid chromatography analysis of vesicle fluids showed that the drugs were taken up rapidly by the parasite. Transmission electron microscopic investigation of parasite tissues and nuclear magnetic resonance spectroscopy of vesicle fluids demonstrated that albendazole sulfoxide and albendazole sulfone had similar effects with respect to parasite ultrastructure and changes in metabolites in vesicle fluids. This study shows that the in vitro cultivation model presented here provides an ideal first-round test system for screening of antiparasite drugs.

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It is not entirely clear when and how steroids should be used to treat trichinellosis.

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Hydatidosis of the bone is a rare form of human echinococcosis. Due to the clinical, diagnostic, therapeutic and prognostic problems involved, the costal and occipital locations are of particular interest. Both are rare and differ from visceral locations in that they are always "primary" and have the capacity to destroy the bone matrix and infiltrate the adjacent tissues. The course of the disease is particularly slow and without specific signs and symptoms so that it can look like any bone condition. Laboratory tests are frequently negative and not wholly specific. While some authors claim that the radiological picture is of no diagnostic significance, others state that it offers pathognomonic signs. Diagnosis will be obtained through the combined assessment of clinical, radiological, laboratory and anamnestic data. Provenance from a rural area should reinforce the suspicion. Surgery, whether radical or conservative, is the key factor in treatment though local recurrences are common. Better results are obtained by combining surgery with Mebendazole for pre and postoperative prophylaxis. Large doses over a long period will give a better clinical course and reduce the incidence of recurrences. The prognosis is good for both sites as long as surgical treatment is given in good time.

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Fifty-three patients with single, multiple and/or multi-organ hydatid cysts were treated with mebendazole, in varying dosages (30-70 mg/kg.day) and over varying periods (6-24 months). Treatment failure was recorded if the mebendazole had no apparent effect on cyst morphology (monitored by radiology, ultrasonography and computed tomography) or only a parasitostatic effect (characterized by mixed and transitory, hypo- and hyper-echoic changes in the lesions). Cure was indicated by a parasitocidal effect (characterized by a totally echogenic picture, increased density of the cyst contents, reduction in the size or complete disappearance of the cysts, complete detachment of the endocysts and/or calcification of the cyst wall). Treatment failure was seen in about 40% of the patients and cure in about 38%; the other 23% had an intermediate result considered as an improvement. Cure rates increased both with dosage and duration, daily dosages of 60-70, 50 and 30-40 mg/kg curing 48%, 33% and 25%, respectively. The pre-treatment condition of any cysts should be taken into consideration when determining dosage and treatment duration.

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vermox 100 mg 2016-08-16

The case report of patient with asymptomatic liver echinococcosis several year observing was shown. The liver cyst occasionally revealed by ultrasound examination had doubled its diameter in two years buy vermox , serological test result had suggested Echinococcus granulosus infection. After the initially treatment with benzimidazole the curative surgery had been conducted and histological examination confirmed the liver echinococcosis diagnosis. The headaches in two years after surgery needed the central nervous system echinococcosis considering in differential diagnostics. Because of the normal liver parenchyma ultrasound image, normal laboratory tests results and negative serological tests results the patient was considered as completely recovered after several year of observation. On the base of procedure undertaken the diagnostics and therapeutic possibilities were reviewed. The necessity of taking the echinococcosis into account in occasionally found liver cysts differential diagnostics and individual choice of the optimal therapeutic schema was underlined.

vermox dosage adults 2017-02-27

Dientamoeba fragilis is a pathogenic protozoan of the human gastrointestinal tract with a worldwide distribution, which has emerged as an important and misdiagnosed cause of chronic gastrointestinal illnesses such as diarrhea and 'irritable-bowel-like' gastrointestinal disease. Very little research has been conducted on the use of suitable antimicrobial compounds. Furthermore, higher rates of co-infection with Enterobius vermicularis have been described, suggesting that E. vermicularis could influence the treatment of D. fragilis-infected patients. To study this, the treatment of E. vermicularis and D. fragilis co-infected patients was evaluated buy vermox .

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A sensitive and specific radioimmunoassay procedure was developed for mebendazole and flubendazole enabling a more thorough study of the systemic absorption and pharmacokinetic behaviour of the drugs. In rats, plasma levels of oral and subcutaneous mebendazole were about 10 times higher than those of flubendazole. The pro-drug R 34 803 showed levels of metabolically formed flubendazole similar to those found for mebendazole. Intramuscular flubendazole in dogs, injected for 5 consecutive days, produced sustained fairly high plasma levels for at least 6 weeks after the last dose. The absorption of oral flubendazole in man was markedly enhanced when the drug was taken Astelin Pediatric Dose together with a meal. A 20-times higher dose, however, produced only an increase by 1.4 of the plasma levels and AUC-values, indicating that the absorption of flubendazole is limited by the extremely poor solubility of the drug in the contents of the gastrointestinal tract.

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The authors present a patient with intestinal lymphangiectasis discussing the pathophysiology, diagnosis and immunologic treatment instituted which was with mebendazole, sulfazalosopyridine and oral calcium. Immunoglobulins and T and B leukocytes showed increase together with clinical improvement in the diarrheal Cozaar 200 Mg picture.

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Dogs and cats become infected with tapeworms by ingesting intermediate hosts that contain encysted juvenile tapeworms called larvae. The dog or cat is said to be the definitive host because it shelters the sexually reproductive, egg-producing stage of the tapeworm. The intermediate hosts, which are vertebrates in the case of Taenia and Mesocestoides and insects in the case of Dipylidium and Hymenolepis, become infected by ingesting unhatched but infective tapeworm eggs discharged in the feces of the dog or cat. The relatively less common Diphyllobothrium and Spirometra tapeworms discharge eggs that are undeveloped when passed in the feces and must fall into water to undergo development to the coracidium stage. Diphyllobothrium and Spirometra may have two or three aquatic intermediate hosts in series. The first of these, a copepod, ingests the free-swimming coracidium or ciliated oncosphere that has hatched from the egg. The final intermediate host containing the larva (plerocercoid) infective for the dog or cat is an aquatic vertebrate (fish, frog, water snake). Thus, dogs and cats become infected with tapeworms by eating uncooked meat or fish or by ingesting certain insects. These intermediate hosts are infected with juvenile tapeworms called larvae, which are the infective form for the dog or cat. The intermediate hosts, in turn, become infected by ingesting tapeworm eggs discharged in the feces of the dog or cat or, in the case of Diphyllobothrium and Spirometra, by ingesting coracidia that have subsequently developed in and hatched from such eggs. By far the most common tapeworms of dogs and cats in North America are D. caninum, T. pisiformis, and T. hydatigena. Therefore, the most common sources of tapeworm infection are, respectively, fleas, wild rabbits, and the uncooked meat and offal of ruminants and swine. Whenever a dose of tapeworm remedy is administered or dispensed, the client should be informed of these potential sources Zovirax Ointment Generic of reinfection. There is considerable overlap in the spectra of activity of currently available cestocides. Mebendazole, fenbendazole, niclosamide, bunamidine, and praziquantel are all effective against Taenia spp. Bunamidine is the drug of choice against Spirometra, Diphyllobothrium, and Mesocestoides. Praziquantel is the drug of choice against Echinococcus and Dipylidium.

vermox 500mg tablet 2016-06-15

The authors present four cases of infection due to Anisakis in an area where people are prone to infectious diseases transmitted Voltaren 5 Gel by raw fish, but in which the presence of this parasite has never been reported. Three of four cases were discovered accidently during surgical procedures for co-existing abdominal pathologies. Raw fish was apparently not involved in all patients. Characteristics of the patients are discussed.

vermox alcohol interaction 2017-02-09

In human echinococcosis, today as in the past, surgical removal of the parasite remains the treatment of choice. Beside certain conditions, adjuvant Avodart Online Prescription chemotherapy with Vermox is indicated for echinococcus multilocularis as well as echinococcus granulosus. A substantial decrease of the echinococcal parasite mass under Mebendazole is not yet known. Nevertheless jaundiced patients with diffuse liver infestation with echinococcus multilocularis became jaundice-free and able to work. Mebendazole toleration is very good. A closely interrelated medical control of patients under Mebendazole therapy ought to be interdisciplinarily carried through between internists and surgeons.